Sodium channels are ion channels that transport sodium ions across cellular membranes. Sodium channels are generally either ligand-gated or voltage-gated. In voltage-gated sodium channels, as in other ...
Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their ...
Nat Clin Pract Neurol. 2008;4(3):159-169. Drug Primary clinical use Protective effect during administration in animal models? Effects of withdrawal in EAE Clinical study Phenytoin Treatment of ...
A new study on live tissue cells is the first to reveal how channels that allow sodium to enter into breast cancer cells enable tumours to grow and spread. The discovery adds to evidence which ...
New research explains how low levels of the electrolyte sodium in the blood can disrupt the timing of the heartbeat in patients taking widely used rhythm-control medications such as flecainide, which ...
Nat Clin Pract Neurol. 2008;4(3):159-169. A 3-year follow-up study of patients with MS treated with sodium channel blockers for neuropathic pain or other paroxysmal symptoms revealed adverse effects ...