Researchers uncover a redox-regulated mechanism that determines whether bone fractures heal or progress to non-union.

Scientists show that neutralizing liver-derived ApoE protein reverses age-related delays in bone fracture healing ...

Bone marrow adipocytes (BMAds) are situated within the bone microenvironment, in close proximity to bone cells, vascular structures, and hematopoietic tissues. The shift of bone marrow stromal/stem ...

When skin tissue is wounded, our blood starts clotting as part of the healing process. Scientists have now developed a blood-based implant that supercharges this mechanism for bigger repair projects: ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

Schematic diagram illustrating how transplanted young mitochondria activate the AKAP1/cAMP/PKA pathway in aged PDLSCs, restoring mitochondrial membrane potential (ΔΨm), reducing ROS, and enhancing ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into ...

Imagine a bruise that never heals — instead, it hardens into bone. A small swelling that doesn’t fade but permanently locks a ...

Schematic overview of the TH-PDA@Mg preparation steps (top), animal experiments (middle), and bone repair mechanisms (bottom). Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of ...