The immune system relies on specialized “effector” T cells to fight off pathogens. However, in chronic infections such as cancer or HIV, the perpetual activation of these cells can turn them into ...

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain. During development, all the specialized neurons in the ...

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...

“Our findings suggest a role for NSD2 in maintaining MM cell identity, with potential implications for future therapeutic strategies based on targeting of NSD2.” “Our findings suggest a role for NSD2 ...

Mesenchymal drift may help explain how cells lose stable identity and acquire pro-fibrotic, inflammatory mesenchymal traits ...

A cell on its way to becoming skin pigment, blood, or nerve does not make that shift alone. It responds to a dense web of molecular instructions, some pushing forward, others holding it back.