New CRISPR paradigm: HKUST scientists created a DNA-guided Cas12a system that targets RNA, reversing the traditional RNA-guided DNA model. Practical advantages: The DNA guides are more stable, cheaper ...
R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...
Historic same-day advances: Two major genetics breakthroughs were revealed: a vast blood protein genetics study and a DNA-guided CRISPR system for RNA targeting. Why it matters: The findings could ...
In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...
A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched. The technology has largely been tested in cells ...
Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...
Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...
ITHACA, N.Y. – A team of ecologists and engineers from Cornell University have made a breakthrough in understanding environmental DNA (eDNA) movement in water. Researchers developed synthetic DNA that ...
Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...
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