One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

Deep in coastal mangroves and even inside our own mouths, biologists are finding that DNA does not always sit in a simple ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

New research led by researchers at the University of California, San Diego (UCSD), School of Medicine, reveals a novel map that depicts the human body’s system for addressing and repairing DNA ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...