A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's ...

RIVERSIDE, Calif. - A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists at Martin Luther University Halle-Wittenberg (MLU) and TU Berlin have published ...

Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

A massive transmembrane complex, γ-secretase churns out the infamous peptides that can start a person on the path in Alzheimer’s disease. Aβ is produced when the secretase shaves three residues at a ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists have investigated a multi-enzyme complex that plays an essential role in metabolism ...

Biological cells invest much of their resources into the production of enzymes, which catalyze the conversion of substrates into products. An international team of bioinformaticians and biophysicists ...

As demand intensifies for "green chemistry" standards across the pharmaceutical and chemical industries, Creative Enzymes—a leading global enzyme technology service provider—today announced the ...

Researchers have used cryo- electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees ...

An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...