Epithelial tissues form selective barriers and undergo complex remodelling throughout embryogenesis and organogenesis. Central to these processes are specialised intercellular junctions—tight ...

Cadherins are transmembrane glycoproteins that mediate calcium-dependent homophilic adhesion between epithelial cells, forming adherens junctions that anchor to the actin cytoskeleton via catenin ...

Our skin and mucous membranes are protected by epithelial cells. This barrier tissue performs its function thanks to specialized structures called junctions. They ensure cell cohesion and regulate ...

Cell-to-cell junctions were visualized by ZO1-GFP, and the dynamics of cell junctions were captured by movies. When the cells indicated by * were spontaneously stretched, a continuous belt of cell ...

Our body consists of ~30 trillion cells. These cells need to tightly attach to each other to maintain the integrity of our body. However, we are constantly exposed to mechanical stress, which ...