In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists have recently identified the mechanism behind regulated splicing of large constitutive exons which ...

Neoantigen screening identifies EGFR L858R mutation immunogenicity in 1862 Chinese NSCLC patients. Using real-world data to investigate time-dependent blood count response to PD-1 and PD-L1 inhibitors ...

A research team led by Prof. XUE Yuanchao from the Institute of Biophysics of the Chinese Academy of Sciences has developed a new method for global profiling of in-situ RNA–RNA contacts associated ...

Many sequences found within mammalian introns closely resemble the specific 5' and 3' splice site consensus signals that regulate exon splicing. It is unclear how the real splice sites are selected ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Clinical Nomogram Using Novel Computed Tomography–Based Radiomics Predicts Survival in Patients With Non–Small-Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy Colorectal cancer (CRC) ...

The human genome is just over 6 feet 8 inches long, which is 2 inches taller than the average NBA basketball player and in total, a lot of nucleotides! But what if the amount of sequence diversity ...

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing—a crucial process for isoform expression and protein diversity—is regulated across different ...

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists from Nagoya University, Japan, led by Associate Professor Akio Masuda, have recently identified the ...