About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple ...
A new study provides insights into the molecular mechanisms of HLA-mediated susceptibility and protection in Goodpasture disease (GPD). This rare renal disorder is characterized by autoimmune ...
About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of ...
A recent study has discovered that B cells mediate spontaneous T cell proliferation through the HLA-DR15 haplotype, and this interaction between T cells and B cells may serve as a key factor in ...
Expert Rev Ophthalmol. 2012;7(6):587-594. Considered all together, the findings of these studies suggest an immunogenetic predisposition to pars planitis, MS and MS-associated uveitis. Although ...
Human CD4+ T-cell epitopes were identified in interferon-beta (IFN-β)-1b. A prominent peptide epitope region was found that induced a proliferative response in 16% of all donors tested. Responses ...
One of the leading triggers for multiple sclerosis (MS) is an infection with the Epstein-Barr virus. However, certain gene variants also play an important role. Researchers at the University of Zurich ...
About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of ...
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