The R2TP complex, a specialised co‐chaperone assembly comprising the AAA+ ATPases RUVBL1 and RUVBL2 along with RPAP3 and PIH1D1, is pivotal in orchestrating the assembly and stabilisation of a wide ...
Preclinical results indicate new approach could be a way to deliver treatment directly to tumors at higher doses, while reducing side effects in healthy tissue.
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