Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

Water makes up around 60 percent of the human body. More than half of this water sloshes around inside the cells that make up organs and tissues. Much of the remaining water flows in the nooks and ...

Now, MIT engineers have found that this "intercellular" fluid plays a major role in how tissues respond when squeezed, pressed, or physically deformed. Their findings could help scientists understand ...

Water makes up around 60% of the human body. More than half of this water is inside the cells that make up organs and tissues, and much of the remaining water flows in the spaces between cells. MIT ...

Developmental biologists have discovered that during egg development in fruit flies, intercellular gaps open between epithelial cells in a controlled way at the points where three cells meet. This ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...

Alterations in peripheral myelin protein 22 (PMP22) gene expression are associated with a host of heritable demyelinating peripheral neuropathies, yet the function of the protein remains unknown.

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...