The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over 260 million cases of coronavirus disease 2019 (COVID-19) along with five million deaths. It has affected different ...
Researchers from Mount Sinai have uncovered a possible explanation for why a flu infection can lead to heart disease. They’ve shown from work with mouse models and human data how the immune system ...
In a recent study published in Science Immunology, researchers investigated whether individuals with breakthrough infections of severe coronavirus disease 2019 (COVID-19) pneumonia demonstrated normal ...
Researchers have discovered that Type I interferon (IFN) plays a key role in helping the immune system effectively target viruses, while stopping white blood cells from 'going rogue' and attacking the ...
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Interferon signal reprograms macrophage mitochondria to promote inflammation resolution, finds study
When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. But it is just as important to resolve that inflammation and return ...
Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.
High serum type I interferon (IFN) scores, measured through six chemokines, correlated with poorer lung function and health-related quality of life in patients with diffuse cutaneous systemic ...
Saphnelo, a human monoclonal antibody, is a type 1 interferon (INF) receptor antagonist that inhibits a key protein in the immune system called the IFNAR receptor. This protein acts like a transmitter ...
New research from The Wistar Institute's Montaner lab—led by Wistar Executive Vice President, director of the HIV Cure and Viral Disease Center, and Herbert Kean, M.D., Family Professor, Luis Montaner ...
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