The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at the base of crypts. While ISCs play an essential role in epithelial ...

Image Caption: The signaling pathways involved in the intestinal stem cell niche and cell fate determination. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and ...

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In ...

Nope, this isn’t a small, prickly mammal with a flashy dye job, but a single intestinal epithelial cell. The colorful, hairlike structures are microvilli, which are designed to maximize the cell’s ...