The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...

While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...

Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent ...

Researchers have found that CAR T-cell therapy can help aging intestines heal by targeting senescent cells. In mice, it ...

Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory cells. Manipulating the enzyme OGDH ...

Many people notice that certain foods become harder to tolerate with age. One possible reason is damage to the intestinal epithelium, a thin, single ...