SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely ...

A recent study posted to the Research Square* preprint server, and currently under consideration at a Nature Portfolio Journal, investigated the specific intracellular signature of severe acute ...

This is a preview. Log in through your library . Abstract Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive cellular processes such as lamellipodial protrusion and ...

An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...

A multimodal imaging study combines cryo-X-ray nanotomography and super-resolution fluorescence microscopy to reveal how protein-coated nanoparticles behave in cells. (Nanowerk Spotlight) The ...

Actin filaments are protein fibers that make up the internal skeleton of the cell. As active elements of our cells, actin filaments support the cell's fusion, movement and are involved in many other ...

Actin filaments — protein structures critical to living movement from single cells to animals — have long been known to have polarity associated with their physical characteristics, with growing ...