Conventionally, antigen receptors are considered to be inactive until engaged by antigen. However, results from many disparate studies indicate that Igα–Igβ-containing complexes such as the pre-B-cell ...

T cells and B cells, which are mainly responsible for regulating acquired immunity, are activated through T cell receptors (TCRs) and B cell receptors (BCRs). Those antigen receptors 'trigger' ...