A research team has successfully demonstrated the world's first gene-editing treatment for Leber's hereditary optic ...

Scientists have discovered a direct cause-and-effect link between faulty mitochondria and the memory loss seen in neurodegenerative diseases. By creating a novel tool to boost mitochondrial activity ...

Investigators have developed a way to 'supercharge' T cells by supplying them with extra mitochondria from multipotent stromal cells. Fighting cancer is exhausting for T cells. Hostile tumor ...

Reduction in mitochondrial activity in multiple sclerosis contributes to Purkinje cell loss. Researchers at the University of California, Riverside (CA, USA) have demonstrated the role mitochondrial ...

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells—cause mitochondrial stress, DNA damage and cell death, Vanderbilt ...

The tumor microenvironment (TME) is a major obstacle that limits effective cancer treatments. Various cells around the tumor promote immunosuppression and prevent the immune system from targeting ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have shown that 5-aminolevulinic acid (5-ALA) helps bypass deficiencies in Complex I (CI), the first in a series of protein complexes that ...

Jeffrey Rathmell, PhD, left, and Darren Heintzman have defined the molecular events of the T cell response to fever temperatures. Fever temperatures rev up immune cell metabolism, proliferation and ...

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...

I always wanted to understand life. What moves us? What allows us to heal and thrive? And what goes wrong when we get sick or when we eventually stop breathing and die? My search for answers to these ...