Researchers discovered that declining levels of phosphatidylcholine may be a major cause of age-related mitochondrial ...

Aging cells lose their energy supply when a single membrane lipid, phosphatidylcholine, fades with age, disrupting ...

Mitochondrial dysfunction manifests as structural damage (swelling, cristae rupture, increased volume/decreased numerical density), energy metabolism abnormalities (reduced COX and Complex I-III ...

Every cell in your body runs on a currency called ATP, and the factories that mint it are mitochondria. For decades, ...

Scientists in the laboratory of Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how mitochondria influence the ...

Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, researchers at the University of Basel, Switzerland, have now gained ...

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear. Research published in the Biophysical Journal shows that ...

When people think about health, they often focus on specific organs like the heart or brain. But many changes related to chronic conditions or ageing begin in the smallest units of your body — your ...

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was ...

Scientists identified phosphatidylcholine loss as a key driver of mitochondrial aging and showed that restoring it can ...