Aminoacylation of transfer RNAs (tRNAs) is essential for protein synthesis. A growing number of human diseases correlate with point mutations in tRNA genes within the mitochondrial genome. These tRNAs ...
Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced ...