MedPage Today

Fighting Primary Biliary Cholangitis: Is This a Potential Partner?

—According to the results of a new international study, there may be a role for insulin-like growth factor-binding protein 4 (IGFBP4) in facilitating the interaction between macrophages and injured ...
Everyday Health

Switching Medications: What to Do if Your Primary Biliary Cholangitis Treatment Isn’t Working

S ince there’s no cure for primary biliary cholangitis (PBC), the main treatment goal is to slow disease progression and ease symptoms, such as itching. The good news is that, for most people, the ...
WebMD

Lynavoy: FDA Approves First Treatment for Severe Itching in Adults With Primary Biliary Cholangitis

What Is Lynavoy, and Why Does It Matter? Lynavoy (linerixibat) is a prescription pill approved by the FDA for treating cholestatic pruritus, a severe, chronic (long-standing), internal (felt under the ...
The American Journal of Managed Care

FDA Approves Linerixibat for Cholestatic Pruritus in Primary Biliary Cholangitis

Linerixibat targets pruritus pathobiology in PBC by blocking ileal bile acid reuptake, aiming to lower circulating pruritogenic bile acid–related mediators. GLISTEN demonstrated greater 24-week WI-NRS ...
Hosted on MSN

Saroglitazar boosts response rates in primary biliary cholangitis

Novel saroglitazar significantly improved biochemical response rates in patients with primary biliary cholangitis (PBC) who had an inadequate response to ursodeoxycholic acid or couldn't tolerate it, ...