EXPORT MECHANISM: The tRNA must mature inside the nucleus before export. tRNAs are aminoacylated, and only tRNAs charged with an amino acid are exported efficiently. Export occurs when the tRNA is ...
Researchers have discovered the first protein quality control system in the yeast nucleus. They report that the system involves an ubiquitin-protein ligase that specifically targets four distinct ...
EPFL researchers have discovered how cells help keep their protein levels steady even when their ability to make new proteins ...
Proteins are among the most important molecular building blocks of life. They are chains of amino acids assembled in our cells by ribosomes, the molecular "protein factories" of our bodies. The ...