What can you do when the biologic you take for your rheumatoid arthritis (RA) doesn’t work or no longer seems effective? First, talk to your rheumatologist to decide if it’s time to switch to a new RA ...

Patients with rheumatoid arthritis (RA) who have an inadequate response to a single TNF inhibitor (TNFi) generally do better if they switch to rituximab, rather than to an alternative TNF inhibitor, ...

Please provide your email address to receive an email when new articles are posted on . PHILADELPHIA — Patients with rheumatoid arthritis frequently switched between JAK inhibitors in Australia, ...

For the first time, a multicentre study has compared the action of two rheumatoid arthritis drugs from the same class. The study established that the two TNF inhibitors investigated are equally ...

Please provide your email address to receive an email when new articles are posted on . MAUI, Hawaii — Findings from the SELECT-COMPARE trial demonstrated that patients with rheumatoid arthritis may ...

For patients with rheumatoid arthritis (RA) for whom a first Janus kinase inhibitor (JAKi) has failed, there appears to be no difference in treatment effectiveness whether the patient is cycled to a ...

Rheumatoid arthritis (RA) is an autoimmune disease, meaning it’s caused by an overactive immune system. Instead of just attacking harmful viruses and bacteria, an immune system with RA attacks your ...

If you have rheumatoid arthritis, your doctor may prescribe a biologic or janus kinase (JAK) inhibitor. Both of these medicines dampen an overactive immune system, which is your body’s defense system ...

JAK inhibitors, a new class of tsDMARDs, have shown superior efficacy in RCTs for RA compared to other biologics. Real-world studies highlight JAK inhibitors' benefits in clinical disease activity, ...

The U.S. Food and Drug Administration (FDA) first approved JAK inhibitors in 2012. “JAK inhibitors are the newest to the scene but have proven benefit in terms of reducing pain, improving function, ...

The management of rheumatoid arthritis (RA) has undergone tremendous changes in the past decade, and is now based on certain guiding principles (Box 1). Most pertinent to the discussion that follows ...

What is the best rheumatoid arthritis therapy after failure of a first anti-TNF drug? No consensus has been reached on whether to switch to rituximab or an alternative TNF inhibitor. New observational ...