The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...

Why do some brains crave more stimulation than others? Learn about dopamine, genetics, and brain function, and how dopamine ...

Autistic adults show reduced availability of a key glutamate receptor, mGlu5, across widespread brain regions.

Yale School of Medicine (YSM) scientists have discovered a molecular difference in the brains of autistic people compared to ...

Nerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Researchers at the NYU Pain Research Center have found a new receptor for ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to ...

Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...