Spatial metabolomics maps the small molecules and lipids that reflect cellular function in real time, a layer inaccessible to transcriptomic or proteomic profiling. Mass spectrometry imaging (MSI) ...

Illumina's spatial transcriptomics offering is slated to provide analyses of millions of cells per experiment across a 50 mm by 15 mm imaging area. (Pixabay) Illumina is raising the curtain on its ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Scientists can now detect molecular features in place at single-cell resolution, but existing spatial transcriptomics technologies remain expensive and difficult for many laboratories to adopt.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Comparison of dose-dense versus standard neoadjuvant chemotherapy for HER2 negative breast cancer: Retrospective, multicenter, real-world, Japanese study (JONIE5). MRI concentric partial response ...

Lee and colleagues present one of the first high-resolution spatial transcriptomic atlases of human heart failure. Using GeoMx digital spatial profiling, they captured transcriptional data from ...

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...