A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

The eukaryotic spliceosome is a multi-megadalton ribonucleoprotein (RNP) complex found in eukaryotic nuclei that catalyzes the removal of introns (non-coding regions) from pre-mRNA and splices exons ...