Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ...

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...

SLAMF6 is an immune cell receptor whose function was not clear. Does it activate or inhibit cells? The results so far have been contradictory. Now, scientists at the Institut de Recherches Cliniques ...

A unique quality of the immune system is that it can generate a ‘memory’ response. This is generally referred to as ‘immune ...

Bacterial vaginosis (BV) is an awfully common—and awful—condition that impacts 1/4 to 1/3 of women worldwide in their lifetime. BV is triggered when the vaginal microbiome, which is normally dominated ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

Explore the evolution of T-cell engagers, from experimental concepts to effective therapies for haematologic malignancies.

Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body? There are instances where killer T cells—which are meant to precisely remove virus-infected ...

Immunotherapy has transformed the field of medicine. In the context of cancer, immune cells become dysregulated and lose the ...