Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated ...

Schematic representation depicts the mechanism by which the ENO2-derived oncometabolite PEP directly binds to HDAC1 and thereby promotes H3K18la, which promotes macrophage polarization and leads to ...

Squamous cell carcinoma treatment varies by stage, involving surgery, radiation, and systemic therapies based on cancer progression and patient health. Stage 1 focuses on tumor removal, Stage 2 ...

Konstanz researchers identify an enzyme that plays a role in the migration of cells in our body—not only during normal tissue formation and wound healing, but also when tumor cells metastasize. This ...

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) larger than normal. Until now, this was considered a sign that the cancer was worsening ...

Daily low-dose aspirin may prevent cancer metastasis by inhibiting platelet activation, thereby enhancing T cell-mediated immunity. This mechanism provides clinicians with a potential biomarker-guided ...

SCLC diagnosis involves imaging, biopsies, and lab tests to assess tumor spread and guide treatment decisions. Treatment options vary by stage, with surgery, chemotherapy, radiation, and immunotherapy ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

An Indian review reveals how macrophages are reprogrammed inside breast tumours, helping cancer grow and spread while opening new treatment pathways.

Please provide your email address to receive an email when new articles are posted on . A genomic test predicts individual risk for metastasis after a cutaneous squamous cell carcinoma diagnosis. Two ...