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  1. Lead compound - Wikipedia

    A lead compound may arise from a variety of different sources. Lead compounds are found by characterizing natural products, employing combinatorial chemistry, or by molecular modeling as in …

  2. Definition of lead compound - NCI Dictionary of Cancer Terms

    In medicine, a chemical compound that shows promise as a treatment for a disease and may lead to the development of a new drug. Thousands of compounds are tested in the laboratory to find a lead …

  3. The effects of lead are the same regardless of the route of exposure (inhalation or oral) and are correlated with internal exposure, as blood lead levels. For this reason, blood lead levels are often …

  4. What are lead compounds? - synapse.patsnap.com

    May 21, 2025 · A lead compound is a chemical compound that demonstrates the desired biological or pharmacological activity in preliminary tests and has the potential to be developed into a drug.

  5. 1.3: What are Properties of Hit and Lead Compounds?

    Although a significant amount of time and resources are usually invested into identifying a lead compound, they usually serve as starting points for large scale chemical optimization to evolve into …

  6. What is a Lead Compound - Beckman

    What is a lead compound? A lead compound is a biologic representative of a compound series (molecules or chemical compounds) with sufficient potential (measured by potency, selectivity, …

  7. What is a Lead Compound? | Lead Compound - cancerscience.net

    What is a Lead Compound? A lead compound is a chemical compound that has shown promising biological or pharmacological activity in preliminary testing and is considered a starting point for …

  8. Compounds of Lead - an overview | ScienceDirect Topics

    Lead compounds are chemical compounds that exhibit desired pharmacologic activity against relevant therapeutic targets and serve as base structures for drug optimization.

  9. Lead compound - Wikiwand

    A lead compound in drug discovery is a chemical compound that has pharma­co­logical or biological activity likely to be therapeutically useful, but may never­t...

  10. Lead compounds - Wikipedia

    Lead (II) forms a series of complexes with chloride, the formation of which alters the corrosion chemistry of the lead. This will tend to limit the solubility of lead in saline media.