Protamine sulfate is usually administered to reverse the large dose of heparin administered during certain surgeries, especially heart surgery where anti-coagulation is necessary to prevent clot …

May 8, 2023 · Protamine is a medication used to reverse and neutralize the anticoagulant effects of heparin. Protamine is the specific antagonist that neutralizes heparin-induced anticoagulation.

Jan 28, 2024 · Easy-to-read patient leaflet for Protamine. Includes indications, proper use, special instructions, precautions, and possible side effects.

Apr 10, 2025 · Protamine sulfate is routinely administered to reverse the systemic anticoagulation effects of unfractionated heparin (UFH) after cardiac surgery or surgical and percutaneous vascular …

Jun 28, 2021 · Protamine (Protamines) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources.

Medscape - Indication-specific dosing for (protamine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Oct 30, 2023 · Protamine is an anticoagulant reversal agent that helps to stop bleeding caused by heparin. Protamine is typically given in a hospital setting as an intravenous (IV) injection over 10 …

Protamine: neutralization of heparin. Strongly basic protamine + strongly acid heparin -> forms stable salt -> removed by reticuloendothelial system.

Protamine is a strongly basic polypeptide used in the reversal of unfractionated heparin. It binds to the highly acidic heparin molecules to form a stable salt that lacks anticoagulant properties.

What is this medication? PROTAMINE (PROH tuh meen) treats heparin overdose. It is often used to reverse the effects of heparin during a procedure. This decreases the risk of bleeding. Cleveland …