What are “hope molecules” ? They’re myokines such as: • BDNF (Brain-Derived Neurotrophic Factor) – supports brain repair, neuroplasticity, mood elevation • Irisin – linked to reduced depression and improved metabolic health • IL-6 (in its exercise-released form) – reduces inflammation and helps energy balance • Myonectin, Myostatin, Cathepsin B, and others involved in mood, metabolism, and stress resilience These molecules cross the blood–brain barrier and signal the brain to create new neurons,